Medication interactions with alcohol
| Medication | Effects |
| disulfiram | flushing diaphoresis, vomiting, headache, confusion |
| anticoagulants | increased anticoagulation after acute alcohol use; decreased with chronic alcohol use |
| griseofulvin | minor disulfiram-like reaction |
| metronidazole | minor disulfiram-like reaction |
| oral hypoglycemics | minor disulfiram-like reaction |
| tranquilizers, narcotics, antihistamine | increased CNS depression |
| diazepam | increased diazepam absorption; increased CNS depression |
| phenytoin | increased anticonvulsant effect with acute alcohol use; with chronic alcohol use it may lower seizure threshold |
| salicylates, NSAIDs | gastrointestinal bleeding |
| chlorpromazine | increased alcohol levels |
| cimetadine | increased alcohol levels |
| MAOI | hypertensive crisis, perhaps from tyramine in some beverages |
Adapted from
Textbook
of Psychosomatic Medicine